Prosaposin Antikörper
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- Target Alle Prosaposin (PSAP) Antikörper anzeigen
- Prosaposin (PSAP)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Prosaposin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Spezifität
- Reacts with human Saposin-B
- Kreuzreaktivität (Details)
- May cross react with proteins from other species due to sequence homology
- Aufreinigung
- Purified (protein A)
- Immunogen
- Synthetic peptide derived from an internal domain of human PSAP
- Top Product
- Discover our top product PSAP Primärantikörper
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- Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:200 - 1:1 000 WB1:500 - 1:5 000 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Must be reconstituted in distilled water to reach 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Haltbarkeit
- 24 months
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- Target
- Prosaposin (PSAP)
- Andere Bezeichnung
- Proactivator Polypeptide Domain Saposin-B (PSAP) (PSAP Produkte)
- Synonyme
- GLBA antikoerper, SAP1 antikoerper, AI037048 antikoerper, SGP-1 antikoerper, SGP1A antikoerper, cb759 antikoerper, wu:fa14a06 antikoerper, wu:fb36e02 antikoerper, wu:fb58g07 antikoerper, PSAP antikoerper, PSP-A antikoerper, SFTPA1B antikoerper, SP-A antikoerper, prosaposin antikoerper, surfactant protein A1 antikoerper, PSAP antikoerper, Psap antikoerper, psap antikoerper, LOC100011417 antikoerper, LOC100304726 antikoerper, LOC100526719 antikoerper, SFTPA1 antikoerper
- Hintergrund
- The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase and galactosylceramide by beta-galactosylceramidase. Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A, GM1 gangliosides by beta-galactosidase and globotriaosylceramide by alpha-galactosidase A. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator.
- Gen-ID
- 5660
- UniProt
- P07602
- Pathways
- Positive Regulation of Endopeptidase Activity
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