SLC2A5 Antikörper (Middle Region)

Produktnummer ABIN4886727

Produktdetails anti-SLC2A5 Antikörper

Target: SLC2A5 (Solute Carrier Family 2 (Facilitated Glucose/fructose Transporter), Member 5 (SLC2A5))

Bindungsspezifität: AA 223-259, Middle Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC2A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 5(SLC2A5) detection. Tested with WB, IHC-P in Human,Rat.

Sequenz: QKKDEAAAKK ALQTLRGWDS VDREVAEIRQ EDEAEKA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 5(SLC2A5) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: solute carrier family 2 (facilitated glucose/fructose transporter), member 5
Protein Name: Solute carrier family 2, facilitated glucose transporter member 5

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SLC2A5 (223-259aa QKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEAEKA), different from the related mouse and rat sequences by nine amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-SLC2A5 Antikörper (ABIN4886727)

Li, Byrd, Doh, Dixon, Lee, Tiwari, Ecelbarger: "Absence of renal enlargement in fructose-fed proximal-tubule-select insulin receptor (IR), insulin-like-growth factor receptor (IGF1R) double knockout mice." in: Physiological reports, Vol. 4, Issue 23, (2018) (PubMed).

Details zu SLC2A5

Target: SLC2A5 (Solute Carrier Family 2 (Facilitated Glucose/fructose Transporter), Member 5 (SLC2A5))

Andere Bezeichnung: SLC2A5 (SLC2A5 Produkte)

Synonyme: GLUT-5 antikoerper, GLUT5 antikoerper, AI526984 antikoerper, Glut5 antikoerper, Slc5a antikoerper, glut5 antikoerper, slc2a7 antikoerper, fb58f04 antikoerper, wu:fb58f04 antikoerper, solute carrier family 2 member 5 antikoerper, solute carrier family 2 (facilitated glucose/fructose transporter), member 5 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 5 antikoerper, solute carrier family 2, facilitated glucose transporter member 5 antikoerper, SLC2A5 antikoerper, Slc2a5 antikoerper, LOC489640 antikoerper, slc2a5 antikoerper

Hintergrund: SLC2A5, also known as GLUT5 (Glucose transporter 5), is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The GLUT5 gene is located on chromosome 1. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient.

Synonyms: Glucose Transporter 5 | GLUT5 | GLUT-5 | GTR5 | SLC 2A5 | SLC2A5 | P22732

Gen-ID: 6518

UniProt: P22732