GABRB3 Antikörper (AA 400-411)

Produktnummer ABIN462296

Produktdetails anti-GABRB3 Antikörper

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Bindungsspezifität: AA 400-411

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Affe, Hamster

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GABRB3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human GABRB3. This antibody is expected to recognize both reported isoforms (NP_000805.1, NP_068712.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Cat, Dog, Horse (100%) Bovine, Rabbit, Pig, Lizard (92%) Opossum, Turkey, Platypus (83%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-EKTAKAKNDRSK from an internal region of human GABRB3 (NP_000805.1, NP_068712.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Cat, Dog, Horse (100%), Bovine, Rabbit, Pig, Lizard (92%), Opossum, Turkey, Platypus (83%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:8000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL. Peptide ELISA: antibody detection limit dilution 1:8000.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu GABRB3

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Andere Bezeichnung: GABRB3 (GABRB3 Produkte)

Synonyme: GABRB3 antikoerper, eca5 antikoerper, LOC100230475 antikoerper, ECA5 antikoerper, A230092K12Rik antikoerper, AW049585 antikoerper, Cp1 antikoerper, Gabrb-3 antikoerper, beta3 antikoerper, gamma-aminobutyric acid type A receptor beta3 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, beta 3 antikoerper, gamma-aminobutyric acid type A receptor beta 3 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 antikoerper, GABRB3 antikoerper, gabrb3 antikoerper, Gabrb3 antikoerper

Hintergrund: Name/Gene ID: GABRB3
Subfamily: GABA A receptor
Family: Ion Channel

Synonyms: GABRB3, Cleft palate 1, Cp1, GABAA receptor beta-3 subunit, GABA(A) receptor, beta 3, ECA5, GABA A receptor beta 3

Gen-ID: 2562

NCBI Accession: NP_000805, NP_068712

UniProt: P28472

Pathways: Sensory Perception of Sound