LNX1 Antikörper
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- Target Alle LNX1 Antikörper anzeigen
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LNX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects LNX1, expressed in heart, placenta, kidney, pancreas and brain.
- Aufreinigung
- Affinty chromatography
- Immunogen
- Synthetic peptide derived from the human LNX1 protein
- Top Product
- Discover our top product LNX1 Primärantikörper
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- Applikationshinweise
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Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Target
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
- Andere Bezeichnung
- LNX1 (LNX1 Produkte)
- Synonyme
- LNX1 antikoerper, fj78f06 antikoerper, lnx antikoerper, si:dkey-12h2.1 antikoerper, wu:fj78f06 antikoerper, zgc:152906 antikoerper, Lnx antikoerper, LNX antikoerper, MPDZ antikoerper, PDZRN2 antikoerper, ligand of numb-protein X 1 antikoerper, LNX1 antikoerper, lnx1 antikoerper, Lnx1 antikoerper
- Hintergrund
- LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.Synonyms: E3 ubiquitin-protein ligase LNX, LNX, LNX-1, Ligand of Numb-protein X 1, Numb-binding protein 1
- Gen-ID
- 84708
- NCBI Accession
- NP_001119800
- UniProt
- Q8TBB1
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