ITPR2 Antikörper (AA 1152-1164)

Produktnummer ABIN461932

Produktdetails anti-ITPR2 Antikörper

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Bindungsspezifität: AA 1152-1164

Reaktivität: Human, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ITPR2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human ITPR2. No cross-reactivity expected with other types of ITPR.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Panda, Bat, Dog, Bovine, Rabbit, Horse, Pig, Opossum (92%) Turkey, Chicken (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-PIEESNILSPVQD from an internal region of human ITPR2 (NP_002214.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Panda, Bat, Dog, Bovine, Rabbit, Horse, Pig, Opossum (92%), Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:128000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu ITPR2

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Andere Bezeichnung: ITPR2 / IP3 Receptor Type 2 (ITPR2 Produkte)

Synonyme: AI649341 antikoerper, InsP3R-2 antikoerper, InsP3R-5 antikoerper, Ip3r2 antikoerper, Itpr5 antikoerper, insP3R2 antikoerper, IP3R2 antikoerper, inositol 1,4,5-trisphosphate receptor type 2 antikoerper, inositol 1,4,5-triphosphate receptor 2 antikoerper, inositol 1,4,5-trisphosphate receptor, type 2 antikoerper, ITPR2 antikoerper, Itpr2 antikoerper

Hintergrund: Name/Gene ID: ITPR2
Subfamily: Inositol 1,4,5-triphosphate receptor
Family: Ion Channel

Synonyms: ITPR2, IP3R 2, InsP3R2, IP3R2, InsP3R type II, IP3 receptor, InsP3R type 2, IP3 receptor isoform 2, Type 2 InsP3 receptor

Gen-ID: 3709

NCBI Accession: NP_002214

UniProt: Q14571

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma