SERPIND1 Antikörper

Produktnummer ABIN458146

Produktdetails anti-SERPIND1 Antikörper

Target: SERPIND1 (serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPIND1 Antikörper ist unkonjugiert

Applikation: Immunodiffusion (ID), Immunoelectrophoresis (IEP), Radial Immunodiffusion (RID)

Spezifität: The antiserum does not cross react with any other component of human plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. of this antiserum has not been tested in detail.

Produktmerkmale: Precipitating polyclonal rabbit antiserum to human heparin cofactor II

Aufreinigung: Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other plasma proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.

Immunogen: Heparin cofactor II is a glycoprotein synthesized in the liver and has a molecular weight of 65,000. It is a plasma serine inhibitor of thrombin. Antithrombin III is more slowly inhibited. A hereditary form of inactive heparin cofactor II has been described. Reduced plasma values have been observed in disseminated intravascular coagulopathy and in lever disease. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: In precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion to identify the presence of heparin cofactor II in human plasma or other body fluids or to determine its concentration. The presence of non-precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in non-precipitating antibody-binding techniques if proper controls are included.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum. No foreign proteins added. Antibody titre: Measured by quantitative precipitin analysis. The amount of heparin cofactor II precipitated by 1 ml an

Buffer: Delipidated, heat inactivated, lyophilized, stable whole antiserum

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by add ing 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.

Details zu SERPIND1

Target: SERPIND1 (serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1))

Andere Bezeichnung: Heparin Cofactor II (SERPIND1 Produkte)

Synonyme: D22S673 antikoerper, HC2 antikoerper, HCF2 antikoerper, HCII antikoerper, HLS2 antikoerper, LS2 antikoerper, THPH10 antikoerper, serpind1 antikoerper, MGC53936 antikoerper, rls2var1 antikoerper, AA985900 antikoerper, AI303446 antikoerper, Hcf2 antikoerper, serpin family D member 1 antikoerper, serpin peptidase inhibitor, clade D (heparin cofactor), member 1 L homeolog antikoerper, serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade D, member 1 antikoerper, SERPIND1 antikoerper, serpind1.L antikoerper, Serpind1 antikoerper, serpind1 antikoerper

Hintergrund: The reactivity of the antiserum is restricted to heparin cofactor II. In bidimensional electrophoresis against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified immunogen. No reaction is obtained with any other plasma protein component or serum