Endothelin-1 Receptor Antikörper (AA 132-162)

Produktnummer ABIN452933

Produktdetails anti-Endothelin-1 Receptor Antikörper

Target: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Bindungsspezifität: AA 132-162

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin-1 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects Human Endothelin A receptor at Center. Other species not tested.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected between aa 132-162 amino acids from the Center region of Human EDNRA

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Endothelin-1 Receptor

Target: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Andere Bezeichnung: Endothelin A Receptor (EDNRA Produkte)

Synonyme: ET-A antikoerper, ETA antikoerper, ETA-R antikoerper, ETAR antikoerper, ETRA antikoerper, hET-AR antikoerper, ET-AR antikoerper, Endor antikoerper, Eta antikoerper, RGD1559432 antikoerper, ETa antikoerper, Gpcr10 antikoerper, ednr-a antikoerper, ednra antikoerper, wu:fb75g12 antikoerper, ednraa antikoerper, eta antikoerper, etar antikoerper, etra antikoerper, zgc:85942 antikoerper, endothelin receptor type A antikoerper, endothelin receptor type Aa antikoerper, endothelin receptor type A L homeolog antikoerper, endothelin receptor type Ab antikoerper, EDNRA antikoerper, Ednra antikoerper, ednraa antikoerper, ednra.L antikoerper, ednra antikoerper, ednrab antikoerper

Hintergrund: EDNRA is a receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Function: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 Cellular Location: Cell membrane, Multi-pass membrane protein. Tissue Location: Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.Synonyms: EDNRA, ET-A, ETA, ETA-R, ETRA, Endothelin-1 receptor, endothelin receptor type A, hET-AR

Molekulargewicht: 48722 Da

Gen-ID: 1909

NCBI Accession: NP_001948

UniProt: P25101

Pathways: cAMP Metabolic Process