Tyrosine Hydroxylase Antikörper (pSer19)

Produktnummer ABIN401584

Produktdetails anti-Tyrosine Hydroxylase Antikörper

Target: Tyrosine Hydroxylase (TH)

Bindungsspezifität: pSer19

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Spezifität: Antibody AP09482PU detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at Serine 19.

Aufreinigung: Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine19 (A-V-Sp-E-Q).

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1/100approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at-20 °C.

Details zu Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Andere Bezeichnung: Tyrosine 3-Monooxygenase (TH) (TH Produkte)

Synonyme: DYT14 antikoerper, DYT5b antikoerper, TYH antikoerper, The antikoerper, CG10118 antikoerper, DH65B antikoerper, DTH antikoerper, Dmel\\CG10118 antikoerper, Pale antikoerper, Ple antikoerper, TH antikoerper, Th antikoerper, VII antikoerper, dTH1 antikoerper, dTH65B antikoerper, pale/ple antikoerper, th antikoerper, dyt14 antikoerper, dyt5b antikoerper, tyh antikoerper, tyrosine hydroxylase antikoerper, pale antikoerper, tyrosine 3-monooxygenase antikoerper, tyrosine hydroxylase S homeolog antikoerper, TH antikoerper, Th antikoerper, ple antikoerper, th antikoerper, th.S antikoerper, LOC100008895 antikoerper

Hintergrund: Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's diseaseSynonyms: TYH, Tyrosine 3-hydroxylase

Gen-ID: 7054

NCBI Accession: NP_000351

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour