CXCL2 Antikörper (C-Term)

Produktnummer ABIN401516

Produktdetails anti-CXCL2 Antikörper

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CXCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: c-KKIIEKMLKN GKSN

Spezifität: This antibody detects CXCL2 / MIP-2 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptid

Immunogen: Peptide from the C-Terminus of the protein sequence according to NP_002080.1. Genename: CXCL2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.2-0.6 μg/mL. Approx 17Da band observed in Human Duodenum lysates(calculated MW of 11.4 kDa according to NP_002080.1).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CXCL2

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Andere Bezeichnung: CXCL2 / MIP2A (CXCL2 Produkte)

Synonyme: CINC-2a antikoerper, GRO2 antikoerper, GROb antikoerper, MGSA-b antikoerper, MIP-2a antikoerper, MIP2 antikoerper, MIP2A antikoerper, SCYB2 antikoerper, GRO3 antikoerper, Gro2 antikoerper, MIP-2 antikoerper, Mgsa-b antikoerper, Mip2 antikoerper, Scyb antikoerper, Scyb2 antikoerper, Mip-2 antikoerper, GROB antikoerper, MIP-2alpha antikoerper, C-X-C motif chemokine ligand 2 antikoerper, chemokine (C-X-C motif) ligand 2 antikoerper, CXCL2 antikoerper, Cxcl2 antikoerper

Hintergrund: The GRO gene was originally identified by subtractive hybridization studies between normal and tumorigenic Chinese hamster embryo fibroblasts. The hamster cDNA was cloned and used as a probe for cloning of the human GRO cDNA. The GROalpha gene initially cloned from T24 cells and the gene in melanoma cells encoding melanoma growth stimulating protein (MGSA) are identical. Human cells contain three closely related, but distinct GRO genes: GRO alpha, GRO beta, and GRO gamma. GRO beta and GRO gamma share 93 % and 82 % identity, respectively, with GRO alpha at the nucleotide level. GROs are members of the chemokine alpha family that is characterized by the separation with one amino acid of the first two cysteine residues, C-X-C, in the amino acid sequence. The GRO gene has been mapped to chromosome 4q21. In normal cells, human mRNA GRO expression is found in foreskin fibroblasts, synovial fibroblasts, chondrocytes and osteocytes. Additionally, GRO mRNA has been detected in mammary fibroblasts, mammary epithelial cells, endothelial cells, activated monocytes, macrophages, and neutrophils. Characterization of the GROalpha receptor indicates the presence of low and high affinity receptors on human neutrophils.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2

Gen-ID: 2920

NCBI Accession: NP_002080

UniProt: P19875

Pathways: Cellular Response to Molecule of Bacterial Origin