Influenza Polymerase Acidic Antikörper (AA 250-300)

Produktnummer ABIN398948

Produktdetails anti-Influenza Polymerase Acidic Antikörper

Target: Influenza Polymerase Acidic (PA)

Bindungsspezifität: AA 250-300

Reaktivität: Influenza A Virus H1N1

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Influenza Polymerase Acidic Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: H1N1 PA Antibody detects influenza A (H1N1) PA protein.

Aufreinigung: Immunoaffinity chromatography.

Immunogen: KLH-coupled synthetic peptide from AA 250-300 of Influenza A virus PA protein (Genbank: CY040004).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mL.Other Applications: user-optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Referenzen für anti-Influenza Polymerase Acidic Antikörper (ABIN398948)

Pena, Vincent, Loving, Henningson, Lager, Li, Perez: "Strain-dependent effects of PB1-F2 of triple-reassortant H3N2 influenza viruses in swine." in: The Journal of general virology, Vol. 93, Issue Pt 10, pp. 2204-14, (2012) (PubMed).

Bradel-Tretheway, Mattiacio, Krasnoselsky, Stevenson, Purdy, Dewhurst, Katze: "Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors." in: Journal of virology, Vol. 85, Issue 17, pp. 8569-81, (2011) (PubMed).

Details zu Influenza Polymerase Acidic

Target: Influenza Polymerase Acidic (PA)

Andere Bezeichnung: H1N1 PA (PA Produkte)

Synonyme: polymerase antikoerper, polymerase PA antikoerper, PA antikoerper

Substanzklasse: Influenza Protein

Hintergrund: Influenza A (H1N1) virus, a subtype of influenzavirus A, is the most common cause of influenza (flu) in humans. A strain of swine-origin H1N1 was responsible for the 2009 flu pandemic. The Influenza A (H1N1) RNA polymerase consists of one part each of three subunits, PB1, PB2, and PA. PA is a subunit of RNA-dependent RNA polymerase that is essential for cRNA-dependent vRNA synthesis.
H1N1 PA Antibody is developed in rabbit using a KLH-coupled synthetic peptide from residues 250-300 of Influenza A virus PA protein (Genbank: CY040004).