CXCR4 Antikörper (N-Term)

Produktnummer ABIN398647

Produktdetails anti-CXCR4 Antikörper

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Rabbit Anti-CXCR4 Polyclonal Antibody detects endogenous levels of human and mouse CXCR4.Positive Control: Hela, HEK293.

Aufreinigung: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide from N-terminal of human CXCR4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mLOther Applications: user-optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4 (CXCR4 Produkte)

Synonyme: CD184 antikoerper, D2S201E antikoerper, FB22 antikoerper, HM89 antikoerper, HSY3RR antikoerper, LAP3 antikoerper, LCR1 antikoerper, LESTR antikoerper, NPY3R antikoerper, NPYR antikoerper, NPYRL antikoerper, NPYY3R antikoerper, WHIM antikoerper, Cmkar4 antikoerper, PB-CKR antikoerper, PBSF/SDF-1 antikoerper, Sdf1r antikoerper, CXC-R4-B antikoerper, CXCR-4-B antikoerper, cd184 antikoerper, cxcr4 antikoerper, fb22 antikoerper, hm89 antikoerper, hsy3rr antikoerper, lap3 antikoerper, lcr1 antikoerper, lestr antikoerper, npy3r antikoerper, npyr antikoerper, npyrl antikoerper, npyy3r antikoerper, xcxcr4 antikoerper, CXC-R4 antikoerper, CXCR-4 antikoerper, d2s201e antikoerper, whim antikoerper, CXC-R4-A antikoerper, CXCR-4-A antikoerper, xCXCR4 antikoerper, CXCR4 antikoerper, cb403 antikoerper, zgc:109863 antikoerper, cb824 antikoerper, C-X-C motif chemokine receptor 4 antikoerper, chemokine (C-X-C motif) receptor 4 antikoerper, C-X-C motif chemokine receptor 4 S homeolog antikoerper, C-X-C chemokine receptor type 4 antikoerper, C-X-C motif chemokine receptor 4 L homeolog antikoerper, chemokine (C-X-C motif), receptor 4b antikoerper, chemokine (C-X-C motif) receptor 4a antikoerper, CXCR4 antikoerper, Cxcr4 antikoerper, cxcr4.S antikoerper, cxcr4 antikoerper, LOC100049444 antikoerper, cxcr4.L antikoerper, cxcr4b antikoerper, cxcr4a antikoerper

Hintergrund: CXCR4 is one member of G-protein coupled receptor that contains seven transmembrane spanning. CXCR4 is a principal coreceptor for T cell tropic strains of HIV1 fusion and entry of human white blood cells. It is also required for the infection by dual-tropic strains of HIV1 and mediates CD4 independent infection by HIV2. Chemokine SDF1 is the ligand for CXCR4 that prevents infection by T tropic HIV. CXCR4 is highly expressed in brain, heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells.Rabbit Anti-CXCR4 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human CXCR4 (Swiss Prot: P61073).

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events