Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human CAMKK2.
CAMKK antikoerper, CAMKKB antikoerper, 6330570N16Rik antikoerper, AW061083 antikoerper, mKIAA0787 antikoerper, camk2b antikoerper, fj90d04 antikoerper, wu:fj90d04 antikoerper, si:dkey-174n20.2 antikoerper, CAMKK2 antikoerper, calcium/calmodulin dependent protein kinase kinase 2 antikoerper, calcium/calmodulin-dependent protein kinase kinase 2, beta antikoerper, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antikoerper, calcium/calmodulin dependent protein kinase II beta antikoerper, calcium/calmodulin-dependent protein kinase kinase 2 antikoerper, CAMKK2 antikoerper, Camkk2 antikoerper, camk2b1 antikoerper, CAMK2B antikoerper, camkk2 antikoerper
Hintergrund
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.