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MCA1 Antikörper (C-Term)

MCA1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB18767 unconjugated
Produktnummer ABIN390679
  • Target Alle MCA1 Produkte
    MCA1 (DNA Segment, MCA1, Multiple CA Repeat 1 (MCA1))
    Bindungsspezifität
    AA 242-268, C-Term
    Reaktivität
    Human
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser MCA1 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Ha, M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1.
    Klon
    RB18767
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    MCA1 (DNA Segment, MCA1, Multiple CA Repeat 1 (MCA1))
    Andere Bezeichnung
    MCA1 (MCA1 Produkte)
    Hintergrund
    MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
    Molekulargewicht
    34353
    Gen-ID
    9255
    NCBI Accession
    NP_001135887, NP_001135888, NP_004748
    UniProt
    Q12904
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