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VDAC1 Antikörper (N-Term)
VDAC1
Reaktivität: Human, Maus
WB, IHC (p), FACS
Wirt: Kaninchen
Polyclonal
RB19920
unconjugated
Produktnummer ABIN2840893
Produktdetails anti-VDAC1 Antikörper
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Target
Alle VDAC1 Antikörper anzeigen
VDAC1
(Voltage-Dependent Anion Channel 1 (VDAC1))
Bindungsspezifität
Alle Epitope für VDAC1 Antikörper
AA 1-30, N-Term
Reaktivität
Alle Reaktivitäten für VDAC1 Antikörper
Human, Maus
Wirt
Alle Wirte für VDAC1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für VDAC1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für VDAC1 Antikörper
Dieser VDAC1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für VDAC1 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Homologie
B, Pig, Rb, Rat
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This VDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human VDAC1.
Klon
RB19920
Isotyp
Ig Fraction
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:8000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Referenzen für anti-VDAC1 Antikörper (ABIN2840893)
(ausblenden)
Chu, Goldman, Kelly, He, Waliczek, Kordower : "Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease. " in: Neurobiology of disease , Vol. 69 , pp. 1-14 , (2014 ) (PubMed ).
Details zu VDAC1
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Target
VDAC1
(Voltage-Dependent Anion Channel 1 (VDAC1))
Andere Bezeichnung
VDAC1 (VDAC1 Produkte )
Synonyme
vdac1 antikoerper, VDAC1 antikoerper, 5076 antikoerper, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1 antikoerper, ATVDAC1 antikoerper, T22N4.9 antikoerper, T22N4_9 antikoerper, voltage dependent anion channel 1 antikoerper, PORIN antikoerper, VDAC-1 antikoerper, AL033343 antikoerper, Vdac5 antikoerper, fa13f11 antikoerper, wu:fa13f11 antikoerper, zgc:85830 antikoerper, voltage-dependent anion channel 1 S homeolog antikoerper, voltage-dependent anion channel 1 antikoerper, voltage dependent anion channel 1 antikoerper, vdac1.S antikoerper, vdac1 antikoerper, VDAC1 antikoerper, Vdac1 antikoerper
Hintergrund
VDAC1 forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. The protein may participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Molekulargewicht
30773
Gen-ID
7416
NCBI Accession
NP_003365
UniProt
P21796
Zuletzt angesehen
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