PARP12 Antikörper (C-Term)

Produktnummer ABIN390267

Produktdetails anti-PARP12 Antikörper

Target: PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))

Bindungsspezifität: AA 454-483, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Parp12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of mouse Parp12.

Klon: RB14194

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PARP12 Antikörper (ABIN390267)

Carter, Sykes, Lanning: "Scarless fetal mouse wound healing may initiate apoptosis through caspase 7 and cleavage of PARP." in: The Journal of surgical research, Vol. 156, Issue 1, pp. 74-9, (2009) (PubMed).

Details zu PARP12

Target: PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))

Andere Bezeichnung: Parp12 (PARP12 Produkte)

Synonyme: ARTD12 antikoerper, MST109 antikoerper, MSTP109 antikoerper, ZC3H1 antikoerper, ZC3HDC1 antikoerper, 9930021O16 antikoerper, AA409132 antikoerper, AA536654 antikoerper, PARP-12 antikoerper, Zc3hdc1 antikoerper, PARP12 antikoerper, zc3h1 antikoerper, mst109 antikoerper, mstp109 antikoerper, zc3hdc1 antikoerper, si:ch211-227d19.2 antikoerper, poly(ADP-ribose) polymerase family member 12 antikoerper, poly (ADP-ribose) polymerase family, member 12 antikoerper, poly(ADP-ribose) polymerase family member 12 L homeolog antikoerper, poly (ADP-ribose) polymerase family, member 12a antikoerper, poly [ADP-ribose] polymerase 12 antikoerper, PARP12 antikoerper, Parp12 antikoerper, parp12.L antikoerper, parp12a antikoerper, parp12 antikoerper, LOC100561568 antikoerper

Hintergrund: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

Molekulargewicht: 79917

Gen-ID: 243771

NCBI Accession: NP_766481

UniProt: Q8BZ20