MAP3K1 Antikörper (pThr1383)
Kurzübersicht für MAP3K1 Antikörper (pThr1383) (ABIN389719)
Target
Alle MAP3K1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pThr1383
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Homologie
- M, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This MAP3K1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1400 of human MAP3K1.
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Isotyp
- IgG
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Applikationshinweise
- DB: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "Involvement of the MEKK1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan." in: Cellular signalling, Vol. 22, Issue 6, pp. 968-76, (2010) (PubMed).
: "MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells." in: Diabetes, Vol. 57, Issue 7, pp. 1896-904, (2008) (PubMed).
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: "Involvement of the MEKK1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan." in: Cellular signalling, Vol. 22, Issue 6, pp. 968-76, (2010) (PubMed).
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- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
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Andere Bezeichnung
- MAP3K1
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Hintergrund
- Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
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Molekulargewicht
- 164470
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Gen-ID
- 4214
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NCBI Accession
- NP_005912
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UniProt
- Q13233
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Pathways
- MAPK Signalweg, Interferon-gamma Pathway, Caspase Kaskade in der Apoptose, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
Target
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