MAP3K1 Antikörper (pThr1402)

Produktnummer ABIN6256476

Produktdetails anti-MAP3K1 Antikörper

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Bindungsspezifität: pThr1402

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Phospho-MEKK1 (Thr1402) Antibody detects endogenous levels of MEKK1 only when phosphorylated at Thr1400, which site historically referenced as Thr1402.

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human MEKK1 around the phosphorylation site of Thr1402.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MAP3K1

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Andere Bezeichnung: MAP3K1 (MAP3K1 Produkte)

Synonyme: MAP3K1 antikoerper, Mekk1 antikoerper, MAPKKK1 antikoerper, MEKK1 antikoerper, Mekk antikoerper, ARAKIN antikoerper, ATMEKK1 antikoerper, MAPK/ERK kinase kinase 1 antikoerper, MAPKKK8 antikoerper, T15F16.5 antikoerper, T15F16_5 antikoerper, MEKK antikoerper, MEKK 1 antikoerper, SRXY6 antikoerper, mitogen-activated protein kinase kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase antikoerper, MAPK/ERK kinase kinase 1 antikoerper, MAP3K1 antikoerper, map3k1 antikoerper, Map3k1 antikoerper, MEKK1 antikoerper

Hintergrund:

Description: Component of a protein kinase signal transduction cascade (PubMed:9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624).

Gene: MAP3K1

Molekulargewicht: 161 kDa

Gen-ID: 4214

UniProt: Q13233

Pathways: MAPK Signalweg, Interferon-gamma Pathway, Caspase Kaskade in der Apoptose, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades