MAP3K1 Antikörper (pThr1402)

Produktnummer ABIN7138774

Produktdetails anti-MAP3K1 Antikörper

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Bindungsspezifität: pThr1402

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 1402(T-G-A(p)-G-F) derived from Human MAP3K1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MAP3K1

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Andere Bezeichnung: MAP3K1 (MAP3K1 Produkte)

Synonyme: MAP3K1 antikoerper, Mekk1 antikoerper, MAPKKK1 antikoerper, MEKK1 antikoerper, Mekk antikoerper, ARAKIN antikoerper, ATMEKK1 antikoerper, MAPK/ERK kinase kinase 1 antikoerper, MAPKKK8 antikoerper, T15F16.5 antikoerper, T15F16_5 antikoerper, MEKK antikoerper, MEKK 1 antikoerper, SRXY6 antikoerper, mitogen-activated protein kinase kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase antikoerper, MAPK/ERK kinase kinase 1 antikoerper, MAP3K1 antikoerper, map3k1 antikoerper, Map3k1 antikoerper, MEKK1 antikoerper

Hintergrund:

Background:

Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

Schmutz J., Nature 431:268-274(2004).
Xia Y., Genes Dev. 12:3369-3381(1998).
Vinik B.S., Mamm. Genome 6:782-783(1995)

Aliases: M3K1_HUMAN antibody, MAP3K1 antibody, MAPK/ERK kinase kinase 1 antibody, MAPKKK1 antibody, MEK kinase 1 antibody, MEKK 1 antibody, Mekk antibody, MEKK1 antibody, Mitogen activated protein kinase kinase kinase 1 antibody, Mitogen activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase antibody, Mitogen-activated protein kinase kinase kinase 1 antibody, SRXY6 antibody

UniProt: Q13233

Pathways: MAPK Signalweg, Interferon-gamma Pathway, Caspase Kaskade in der Apoptose, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades