This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This SULT2B1a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SULT2B1a/b.
HSST2 antikoerper, AI326997 antikoerper, BB173635 antikoerper, ST2B1 antikoerper, SULT2B antikoerper, SULT2B1 antikoerper, MGC79784 antikoerper, sulfotransferase family 2B member 1 antikoerper, sulfotransferase family, cytosolic, 2B, member 1 antikoerper, sulfotransferase family 2B member 1 L homeolog antikoerper, SULT2B1 antikoerper, Sult2b1 antikoerper, sult2b1 antikoerper, sult2b1.L antikoerper
Hintergrund
Cytosolic sulfotransferases (STs or SULTs) catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. Her et al. (1998) identified an EST with homology to ST enzymes. By PCR with human placental and prostate cDNA as template, they isolated 2 alternatively spliced cDNAs, identical throughout most of their sequences, but having different 5-prime ends. The shorter cDNA, SULT2B1a, encodes a protein of 350 amino acids, the longer cDNA, SULT2B1b, encodes a 365-amino acid protein. Genomic PCR analysis revealed that the gene encoding both cDNAs, SULT2B1, contains 7 exons, with 2 alternative first exons being used to generate SULT2B1a and SULT2B1b. Northern blot analysis revealed that the SULT2B1 gene is expressed as a 1.4-kb transcript predominantly in prostate, placenta, and trachea.