TIMP4 Antikörper (AA 35-224)

Produktnummer ABIN375604

Produktdetails anti-TIMP4 Antikörper

Target: TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))

Bindungsspezifität: AA 35-224

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Human/Mouse/Rat TIMP-4

Produktmerkmale: Mouse Anti-Human TIMP-4-UNLB

Aufreinigung: Purified

Immunogen: Recombinant human TIMP-4 (a.a. 35-224)

Klon: SB30c

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: WB - Quality tested , ICC , ELISA
• Working Dilutions: Immunoblotting Purified (UNLB) antibody ≤ 2 g/mL HRP conjugate 1:1,000 - 1:2,000

Probenmenge: 0,2 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.1 mg purified immunoglobulin in 0.2 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu TIMP4

Target: TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))

Andere Bezeichnung: TIMP-4 (TIMP4 Produkte)

Synonyme: TIMP4 antikoerper, TIMP-4 antikoerper, timp4 antikoerper, TIMP metallopeptidase inhibitor 4 antikoerper, TIMP metallopeptidase inhibitor 4, tandem duplicate 3 antikoerper, tissue inhibitor of metalloproteinase 4 antikoerper, TIMP4 antikoerper, timp4.3 antikoerper, Timp4 antikoerper

Hintergrund: Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs therefore play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4 (approx. 23 kDa), unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation. It has been shown to be an inhibitor of MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9 with a preference for MMP-2 and MMP-7.