TIMP4 Antikörper (HRP)

Produktnummer ABIN375479

Produktdetails anti-TIMP4 Antikörper (HRP)

Target: TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP4 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale: The antibody detects: Human TIMP-4
To insure lot-to-lot consistency, each batch of product is tested by IHC to conform with the characteristics of a standard reference reagent.

Aufreinigung: Purified

Immunogen: Recombinant TIMP-4

Klon: SB30c

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Details zu TIMP4

Target: TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))

Andere Bezeichnung: TIMP-4 (TIMP4 Produkte)

Synonyme: TIMP4 antikoerper, TIMP-4 antikoerper, timp4 antikoerper, TIMP metallopeptidase inhibitor 4 antikoerper, TIMP metallopeptidase inhibitor 4, tandem duplicate 3 antikoerper, tissue inhibitor of metalloproteinase 4 antikoerper, TIMP4 antikoerper, timp4.3 antikoerper, Timp4 antikoerper

Hintergrund: Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs therefore play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4 (approx. 23 kDa), unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation. It has been shown to be an inhibitor of MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9 with a preference for MMP-2 and MMP-7.