DACH1 Antikörper (Internal Region)

Produktnummer ABIN375187

Produktdetails anti-DACH1 Antikörper

Target: DACH1 (Dachshund 1 (DACH1))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DACH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Dachshund homolog 1. This antibody is expected to recognise all three reported isoforms.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig.
Species reactivity (tested):Human.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography

Immunogen: Peptide with sequence SPVENTPQNNECK, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu DACH1

Target: DACH1 (Dachshund 1 (DACH1))

Andere Bezeichnung: DACH1 (DACH1 Produkte)

Synonyme: DACH antikoerper, AI182278 antikoerper, Dac antikoerper, Dach antikoerper, E130112M23Rik antikoerper, dach antikoerper, dachshund family transcription factor 1 antikoerper, dachshund 1 (Drosophila) antikoerper, dachshund family transcription factor 1 S homeolog antikoerper, dachshund homolog 1 antikoerper, DACH1 antikoerper, Dach1 antikoerper, dach1.S antikoerper, dach1 antikoerper, LOC100550020 antikoerper

Hintergrund: DACH1 is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a member of the Ski gene family and is thought to be involved in eye development. Four alternatively spliced transcripts encoding different isoforms have been described for this gene. (from Entrez gene). DACH1 has also been found to inhibit oncogene-mediated breast tumor growth via downregulation of cyclin D1. Expression of DACH1 has been found to inversely correlate with metastasis.Synonyms: (Drosophila), DACH, DACH-1, Dachshund homolog 1, FLJ10138, OTTHUMP00000040839, RP11-512J14.1

Gen-ID: 1602

NCBI Accession: NP_004383

UniProt: Q9UI36

Pathways: Feeding Behaviour