VTCN1 Antikörper (Internal Region)

Produktnummer ABIN375113

Produktdetails anti-VTCN1 Antikörper

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser VTCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-SKGKGNANLE YK

Spezifität: This antibody recognizes Human B7-H4.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_078902.2. Genename: VTCN1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu VTCN1

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Andere Bezeichnung: VTCN1 / B7H4 (VTCN1 Produkte)

Synonyme: B7h4 antikoerper, B7s1 antikoerper, B7x antikoerper, BC032925 antikoerper, B7-H4 antikoerper, B7H4 antikoerper, B7S1 antikoerper, B7X antikoerper, B7h.5 antikoerper, PRO1291 antikoerper, VCTN1 antikoerper, RGD1311204 antikoerper, V set domain containing T cell activation inhibitor 1 L homeolog antikoerper, V-set domain containing T cell activation inhibitor 1 antikoerper, V-set domain containing T-cell activation inhibitor 1 antikoerper, V set domain containing T cell activation inhibitor 1 antikoerper, vtcn1.L antikoerper, VTCN1 antikoerper, vtcn1 antikoerper, Vtcn1 antikoerper

Hintergrund: B7-H4 is a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity. Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production. B7-H4 deficient mice are only minimally affected, suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response. B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7-H4 could be a useful prognostic marker in Renal Cell Carcinoma (RCC).Synonyms: B7-H4, B7S1, B7h.5, B7x, UNQ659/PRO1291, V-set domain-containing T-cell activation inhibitor 1

Gen-ID: 79679, 9606

UniProt: Q7Z7D3