NDEL1 Antikörper (both Isoforms, Internal Region)

Produktnummer ABIN375101

Produktdetails anti-NDEL1 Antikörper

Target: NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

Bindungsspezifität: both Isoforms, Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NDEL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to NDEL1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence CRNFAKDQASRKSY, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NDEL1

Target: NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

Andere Bezeichnung: NDEL (NDEL1 Produkte)

Synonyme: EOPA antikoerper, MITAP1 antikoerper, NDE1L1 antikoerper, NDE2 antikoerper, NUDEL antikoerper, NUDE2 antikoerper, Nudel antikoerper, 2600006O07Rik antikoerper, mNudel antikoerper, wu:fi23c04 antikoerper, wu:fi23e06 antikoerper, eopa antikoerper, mitap1 antikoerper, ndel1 antikoerper, ndel1-a antikoerper, ndel1-b antikoerper, nudel antikoerper, nudE neurodevelopment protein 1 like 1 antikoerper, nudE neurodevelopment protein 1-like 1 antikoerper, nudE neurodevelopment protein 1-like 1b antikoerper, nudE neurodevelopment protein 1 like 1 L homeolog antikoerper, NDEL1 antikoerper, Ndel1 antikoerper, ndel1b antikoerper, ndel1.L antikoerper

Hintergrund: Nudel is important for normal cortical development. It is invovled in microtubule organization, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50 % identity with mouse and human NUDE proteins.Synonyms: EOPA, MITAP1, NUDEL, Nuclear distribution protein nudE-like 1

Gen-ID: 81565, 9606

UniProt: Q9GZM8

Pathways: Regulation of Cell Size