DPM1 Antikörper (N-Term)

Produktnummer ABIN375033

Produktdetails anti-DPM1 Antikörper

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Bindungsspezifität: N-Term

Reaktivität: Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Dpm1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Rat.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence PQGRSSRQDKYS-C, from the N-Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DPM1

Target: DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))

Andere Bezeichnung: DPM1 (DPM1 Produkte)

Synonyme: DPM1 antikoerper, zgc:101018 antikoerper, MGC114892 antikoerper, AI118379 antikoerper, AI194292 antikoerper, CDGIE antikoerper, MPDS antikoerper, DPMS antikoerper, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit antikoerper, dolichyl-phosphate mannosyltransferase subunit 1, catalytic antikoerper, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog antikoerper, dolichol-phosphate (beta-D) mannosyltransferase 1 antikoerper, dpm1 antikoerper, DPM1 antikoerper, dpm1.S antikoerper, Dpm1 antikoerper

Hintergrund: Dolichol-phosphate mannose (DPM1) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Defective surface expression of GPI-anchored proteins occurs when there is a lack of DPM1. DPM1 is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.Synonyms: DPM synthase, DPM-1, Dolichol-phosphate mannose synthase, Dolichol-phosphate mannosyltransferase, Dolichyl-phosphate beta-D-mannosyltransferase, EC=2.4.1.83, MPD synthase, Mannose-P-dolichol synthase

Gen-ID: 8813

NCBI Accession: NP_003850

UniProt: O60762

Pathways: Inositol Metabolic Process