GRIK3 Antikörper (Internal Region)

Produktnummer ABIN375008

Produktdetails anti-GRIK3 Antikörper

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GRIK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to GRIK3 / GLUR7.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Canine, Bovine.
Species reactivity (tested):Rat, Mouse.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-KIRQLPIDSDDSRP, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-GRIK3 Antikörper (ABIN375008)

Chao, Chen, Liu: "S-allyl L-cysteine protects the retina against kainate excitotoxicity in the rat." in: The American journal of Chinese medicine, Vol. 42, Issue 3, pp. 693-708, (2014) (PubMed).

Details zu GRIK3

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Andere Bezeichnung: GRIK3 / GLUR7 (GRIK3 Produkte)

Synonyme: GRIK3 antikoerper, eaa5 antikoerper, glr7 antikoerper, glur7 antikoerper, 9630027E11 antikoerper, GluK3 antikoerper, GluR7-3 antikoerper, Glur-7 antikoerper, Glur7 antikoerper, GluR7 antikoerper, gluR-7 antikoerper, EAA5 antikoerper, GLR7 antikoerper, GLUR7 antikoerper, GluR7a antikoerper, glutamate ionotropic receptor kainate type subunit 3 antikoerper, glutamate receptor, ionotropic, kainate 3 L homeolog antikoerper, glutamate receptor, ionotropic, kainate 3 antikoerper, GRIK3 antikoerper, grik3.L antikoerper, Grik3 antikoerper

Hintergrund: GRIK3 belongs to the ligand gated ionic channel family and is a receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. The GRIK3 receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. GRIK3 can coassemble with either GRIK4 or GRIK5 to form heteromeric receptors. RNA editing in the mRNA has been reported.Synonyms: EAA5, Excitatory amino acid receptor 5, GluR-7, Glutamate receptor 7, Glutamate receptor ionotropic kainate 3

Gen-ID: 2899

NCBI Accession: NP_000822

UniProt: Q13003

Pathways: Synaptic Membrane