ABCC5
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Peptide ELISA: Detection Limit: 1/32000. Wetsren Blot: 0.5-1.5 μg/mL. Approx.150 kDa band observed in Human Brain (FrnotalCortex) and Mouse Brain lysates. Immunohistochemistry on Paraffin Embedded Sections: 4-6 μg/mL. In paraffin embedded Human Kidney shows membranous staining in DCT. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
ABCC5
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
ABC33 antikoerper, EST277145 antikoerper, MOAT-C antikoerper, MOATC antikoerper, MRP5 antikoerper, SMRP antikoerper, pABC11 antikoerper, 2900011L11Rik antikoerper, AI132311 antikoerper, Abcc5a antikoerper, Abcc5b antikoerper, Mrp5 antikoerper, abc33 antikoerper, abcc5 antikoerper, moat-c antikoerper, moatc antikoerper, mrp5 antikoerper, pabc11 antikoerper, smrp antikoerper, ATP binding cassette subfamily C member 5 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 5 antikoerper, ATP binding cassette subfamily C member 5 L homeolog antikoerper, ABCC5 antikoerper, Abcc5 antikoerper, abcc5.L antikoerper
Hintergrund
MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.Synonyms: ATP-binding cassette sub-family C member 5, MOAT-C, Multi-specific organic anion transporter C, Multidrug resistance-associated protein 5, SMRP, pABC11