C14orf169 + NO66 Antikörper (Internal Region)

Produktnummer ABIN374928

Produktdetails anti-C14orf169 + NO66 Antikörper

Target: C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser C14orf169 + NO66 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to C14orf169 / NO66.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-GAQHSDSKDPR, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu C14orf169 + NO66

Target: C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

Andere Bezeichnung: NO66 (C14orf169 Produkte)

Synonyme: LOC453015 antikoerper, C10H14orf169 antikoerper, MAPJD antikoerper, NO66 antikoerper, ROX antikoerper, C14orf169 antikoerper, No66 antikoerper, im:7141580 antikoerper, no66 antikoerper, chromosome 14 open reading frame 169 antikoerper, ribosomal oxygenase 1 antikoerper, chromosome 5 open reading frame, human C14orf169 antikoerper, LOC453015 antikoerper, Bm1_08415 antikoerper, RIOX1 antikoerper, C5H14ORF169 antikoerper, Riox1 antikoerper, riox1 antikoerper

Hintergrund: C14orf169 is the human homolog of Xenopus xNO66. xNO66 is a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin. It is a novel, ubiquitous protein, which in most cell types appears to be a constitutive nucleolar component. Immunolocalization studies have revealed that this protein is highly conserved during evolution and shows in most cells analyzed a dual localization pattern, i.e., a strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities. Colocalizations with proteins Ki-7, HP1alpha, and PCNA, respectively, have further shown that the staining pattern of xNO66 overlaps with certain clusters of late replicating chromatin. Biochemical experiments have revealed that protein NO66 cofractionates with large preribosomal particles but is absent from cytoplasmic ribosomes. It is proposed that in addition to its role in ribosome biogenesis protein xNO66 has functions in the replication or remodeling of certain heterochromatic regions.Synonyms: C14orf169, Nucleolar protein 66, hsNO66

Gen-ID: 79697

NCBI Accession: NP_078920

UniProt: Q9H6W3