GPX3 Antikörper (Internal Region)

Produktnummer ABIN374849

Produktdetails anti-GPX3 Antikörper

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GPX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-NQFGKQEPGE NSE

Spezifität: This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002075.2.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution: 1/1000. Western Blot: 1-3 μg/mL. Approx 26 kDa band observed in Mouse Kidney and Liver lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GPX3

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Andere Bezeichnung: Glutathione Peroxidase 3 / GPX3 (GPX3 Produkte)

Synonyme: GPX3 antikoerper, DKFZp469D1932 antikoerper, AA960521 antikoerper, EGPx antikoerper, GPx antikoerper, GSHPx-3 antikoerper, GSHPx-P antikoerper, GPx-3 antikoerper, GPx-P antikoerper, Gpxp antikoerper, glutathione peroxidase 3 antikoerper, gpx3 antikoerper, GPX3 antikoerper, Gpx3 antikoerper

Hintergrund: Glutathione peroxidases(Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organichydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPxfamily to be discovered. GPx2, also known as gastrointestinal GPx(GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract.Extracellular plasma GPx(pGPxor GPx3) is mainly expressed by the kidney from where it is released into the blood. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxylipids in low density lipoprotein orthymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site.Synonyms: Extracellular glutathione peroxidase, GPX-3, GPXP, GPx-3, GPx-P, GSHPXP, GSHPx-3, GSHPx-P, Glutathione peroxidase-3, Plasma glutathione peroxidase

Gen-ID: 2878

NCBI Accession: NP_002075

UniProt: P22352

Pathways: Thyroid Hormone Synthesis