VDAC2 Antikörper (Internal Region)

Produktnummer ABIN374727

Produktdetails anti-VDAC2 Antikörper

Target: VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser VDAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes VDAC2.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence C-DSAKSKLTRNN, from the internal region of the protein sequence according to NP_003366.2.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu VDAC2

Target: VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))

Andere Bezeichnung: VDAC2 (VDAC2 Produkte)

Synonyme: POR antikoerper, Vdac6 antikoerper, mVDAC2 antikoerper, mVDAC6 antikoerper, wu:fa01a08 antikoerper, wu:fa98a10 antikoerper, wu:fb50g11 antikoerper, zgc:55795 antikoerper, zgc:77621 antikoerper, vdac2 antikoerper, VDAC2 antikoerper, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2 antikoerper, ATVDAC2 antikoerper, K9I9.6 antikoerper, K9I9_6 antikoerper, voltage dependent anion channel 2 antikoerper, voltage dependent anion channel 2 antikoerper, voltage-dependent anion channel 2 antikoerper, voltage-dependent anion channel 2 S homeolog antikoerper, VDAC2 antikoerper, Vdac2 antikoerper, vdac2 antikoerper, vdac2.S antikoerper

Hintergrund: VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. VDAC2 interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. It consists mainly of membrane spanning sided beta sheets, and belongs to the eukaryotic mitochondrial porin family.Synonyms: Outer mitochondrial membrane protein porin 2, VDAC-2, Voltage-dependent anion-selective channel protein 2

Gen-ID: 7417, 9606

UniProt: P45880