PUM2 Antikörper (Internal Region)

Produktnummer ABIN374533

Produktdetails anti-PUM2 Antikörper

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Schimpanse

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PUM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-DQNRDLKQGD DDDSK

Spezifität: This antibody recognizes Pumilio-2.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence Genename: PUM2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL, Some minor bands are resistant to blocking by the immunizingpeptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PUM2

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Andere Bezeichnung: Pumilio 2 / PUM2 (PUM2 Produkte)

Synonyme: pum-2 antikoerper, 5730503J23Rik antikoerper, Pumm2 antikoerper, mKIAA0235 antikoerper, PUMH2 antikoerper, PUML2 antikoerper, pumilio RNA binding family member 2 antikoerper, pumilio RNA-binding family member 2 antikoerper, pum2 antikoerper, Pum2 antikoerper, PUM2 antikoerper

Hintergrund: Pumilio 2, a human homolog of Pumilio, a protein required to maintain germ line stem cells in Drosophila and Caenorhabditis elegans, forms a stable complex with DAZ through the same functional domain required for RNA binding, protein-protein interactions and rescue of Pumilio mutations in flies. Pumilio 2 is expressed predominantly in human embryonic stem cells and germ cells and colocalizes with DAZ and DAZL in germ cells. Pumilio 2 is a component of conserved cellular machinery that may be required for germ cell development.Synonyms: KIAA0235, PUM-2, PUMH2, Pumilio homolog 2, Pumilio-2

Gen-ID: 23369

NCBI Accession: NP_056132

UniProt: Q8TB72

Pathways: Ribonucleoprotein Complex Subunit Organization