MSX1 Antikörper (N-Term)

Produktnummer ABIN374442

Produktdetails anti-MSX1 Antikörper

Target: MSX1 (Msh Homeobox 1 (MSX1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MSX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: TSLPLGVKVE DS-C

Spezifität: Recognizes MSX1 (N-term).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, and Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the N Terminus of the protein sequence according to NP_002439.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Antibody Detection Limit Dilution: 1/16000. Western blot: Preliminary experiments gave an approx.55-60 kDa band in Human Muscleand Heart lysates at 1 μg/mL. Further, this band was successfully blocked byincubation with the immunising peptide. Please note that currently we cannot find anexplanation in the literature for the band we observe given the predicted size of approx.31.0 kDa according to Human NP_002439.2. Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Prostate shows staining of nucleoli in a few epithelial cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu MSX1

Target: MSX1 (Msh Homeobox 1 (MSX1))

Andere Bezeichnung: MSX1 (MSX1 Produkte)

Synonyme: ECTD3 antikoerper, HOX7 antikoerper, HYD1 antikoerper, STHAG1 antikoerper, AA675338 antikoerper, AI324650 antikoerper, Hox-7 antikoerper, Hox7 antikoerper, Hox7.1 antikoerper, msh antikoerper, CHOX-7 antikoerper, GHOX-7 antikoerper, HOX-7 antikoerper, msh homeobox 1 antikoerper, MSX1 antikoerper, Msx1 antikoerper

Hintergrund: MSX1 is a transcriptional repressor that belongs to the Msh homeobox family. It plays a role in cranofacial development, specifically in odontogenesis. A Sonic hedgehog-controlled cascade that includes MSX1 acts in parallel with the Wnt1 network to establish the midbrain dopaminergic progenitor domain, which gives rise to a neuronal population that is critical for normal function of the human brain and is involved in a number of neurological and psychiatric diseases, such as Parkinson's disease.Synonyms: HOX7, Homeobox protein Hox-7, Homeobox protein MSX-1, Hox-7, MSX-1, Msh homeobox 1-like protein

Gen-ID: 4487, 9606

UniProt: P28360

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus