DEF6 Antikörper (N-Term)

Produktnummer ABIN374432

Produktdetails anti-DEF6 Antikörper

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DEF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALRKELLKSI WYA-C

Spezifität: This antibody recognizes IBP/DEF6.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Pig, Cow, Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the N Terminus of the protein sequence according to NP_071330.3

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Antibody Detection Limit Dilution: 1/2,000. Western Blot: 1-3 μg/mL. Approx.70 kDa band observed in Human Thymus lysates(calculated MW of 73.0 kDa according to NP_071330.3).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DEF6

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Andere Bezeichnung: DEF6 (DEF6 Produkte)

Synonyme: DEF6 antikoerper, Def6 antikoerper, zgc:63721 antikoerper, ibp antikoerper, slat antikoerper, swap70l antikoerper, MGC68775 antikoerper, 2410003F05Rik antikoerper, 6430538D02Rik antikoerper, AV094905 antikoerper, Ibp antikoerper, Slat antikoerper, Slat2 antikoerper, Slat6 antikoerper, IBP antikoerper, SLAT antikoerper, SWAP70L antikoerper, DEF6, guanine nucleotide exchange factor antikoerper, differentially expressed in FDCP 6a homolog (mouse) antikoerper, DEF6, guanine nucleotide exchange factor L homeolog antikoerper, differentially expressed in FDCP 6 antikoerper, DEF6 guanine nucleotide exchange factor antikoerper, DEF6 antikoerper, def6a antikoerper, def6.L antikoerper, def6 antikoerper, Def6 antikoerper

Hintergrund: DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC and CDC42 that is highly expressed in B and T cells. It is a novel PH-DH-like domain protein, and is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.Synonyms: DEF-6, Differentially expressed in FDCP 6 homolog, IBP, IRF4-binding protein, SLAT, SWAP70L

Gen-ID: 50619

NCBI Accession: NP_071330

UniProt: Q9H4E7