MPP5 Antikörper (N-Term)

Produktnummer ABIN374386

Produktdetails anti-MPP5 Antikörper

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Bindungsspezifität: N-Term

Reaktivität: Human, Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MPP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: NKASPPFPLI SNAQ-C

Spezifität: This antibody detects MPP5 at N-term.

Kreuzreaktivität (Details): Species reactivity (expected):Gorilla, Orangutan, Gibbon, Monkey, Bovine, Dog, Horse, Pig, Rabbit.
Species reactivity (tested):Human.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from N Terminus of the protein sequence according to NP_071919.1 Genename: MPP5

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 75 kDa band observed in Human Brain lysate (calculatedMW of 77.5 kDa according to NP_071919). Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Skeletal Muscle showsstrong alternating staning of muscle fibres in longitudinal section.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu MPP5

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Andere Bezeichnung: MPP5 (MPP5 Produkte)

Synonyme: PALS1 antikoerper, 3830420B02Rik antikoerper, AI255216 antikoerper, AI644496 antikoerper, Pals1 antikoerper, mpp5 antikoerper, nok antikoerper, MAGUK p55 subfamily member 5 antikoerper, membrane palmitoylated protein 5 antikoerper, membrane protein, palmitoylated 5 L homeolog antikoerper, membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) antikoerper, membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) antikoerper, Tsp_03061 antikoerper, MPP5 antikoerper, mpp5.L antikoerper, Mpp5 antikoerper, mpp5a antikoerper

Hintergrund: Members of the peripheral membrane associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ/ SH3/ GUK core and are divided into 4 subfamilies (DLG like, ZO1 like, p55 like and LIN2 like) based on their size and the presence of additional domains. MPP5 is a member of the p55 like MAGUK subfamily. The gene product of MPP5 is thought to interact with the LIN7 proteins.Synonyms: MAGUK p55 subfamily member 5

Gen-ID: 64398

NCBI Accession: NP_071919

UniProt: Q8N3R9

Pathways: Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization