SNTA1 Antikörper (N-Term)

Produktnummer ABIN374379

Produktdetails anti-SNTA1 Antikörper

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SNTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: ASGRRAPRTG LLE-C

Spezifität: This antibody detects Alpha-1-syntrophin (SNTA1) at N-term.

Kreuzreaktivität (Details): Species reactivity (expected):Dog, Pig, Cow.
Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from N Terminus of the protein sequence according to NP_003089.1 Genename: SNTA1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection limit dilution 1: 32000. Western Blot: 1-3 μg/mL. Approx 60 kDa band observed in Human Skeletal Muscle lysates(calculated MW of 53.0 kDa according to NP_003089.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu SNTA1

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Andere Bezeichnung: Syntrophin-1 / SNTA1 (SNTA1 Produkte)

Synonyme: SNTA1 antikoerper, MGC147484 antikoerper, AW228934 antikoerper, Snt1 antikoerper, LQT12 antikoerper, SNT1 antikoerper, TACIP1 antikoerper, dJ1187J4.5 antikoerper, syntrophin alpha 1 antikoerper, syntrophin, alpha 1 L homeolog antikoerper, syntrophin, alpha 1 antikoerper, syntrophin, acidic 1 antikoerper, SNTA1 antikoerper, snta1.L antikoerper, snta1 antikoerper, Snta1 antikoerper

Hintergrund: Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.Synonyms: 59 kDa dystrophin-associated protein A1 acidic component 1, Alpha-1-syntrophin, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, SNT1, TACIP1

Gen-ID: 6640

NCBI Accession: NP_003089

UniProt: Q13424

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development