Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (C-Term) Antikörper

Produktnummer ABIN374273

Produktdetails

Target: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: C-RLIVAREHID KYKN

Spezifität: This antibody detects ACADM at C-term. Expected to recognise both reported isoforms.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Synthetic peptide from C-Terminus of Human ACADM protein (NP_000007.1, NP_001120800.1) Genename: ACADM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial

Andere Bezeichnung: ACADM

Synonyme: ACAD1 antikoerper, MCAD antikoerper, MCADH antikoerper, AU018656 antikoerper, acyl-CoA dehydrogenase medium chain antikoerper, acyl-Coenzyme A dehydrogenase, medium chain antikoerper, acyl-CoA dehydrogenase, C-4 to C-12 straight chain antikoerper, ACADM antikoerper, Acadm antikoerper

Hintergrund: ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.Synonyms: MCAD, Medium-chain specific acyl-CoA dehydrogenase mitochondrial

Gen-ID: 34

NCBI Accession: NP_000007

UniProt: P11310