DOK3 Antikörper (C-Term)

Produktnummer ABIN374125

Produktdetails anti-DOK3 Antikörper

Target: DOK3 (Docking Protein 3 (DOK3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DOK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TRERRKGPAP CDRP

Spezifität: This antibody detects Docking protein 3/DOK3 (C-term).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from C Terminus of the protein sequence according to NP_079148.2 Genename: DOK3

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/64000. Western blot: 0.1-0.3 μg/mL. Approx 60 kDa band observed in Human Peripheral BloodMononucleocytes lysates (calculated MW of 53.0 kDa according to NP_079148.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DOK3

Target: DOK3 (Docking Protein 3 (DOK3))

Andere Bezeichnung: DOK3 (DOK3 Produkte)

Synonyme: DOK3 antikoerper, DOKL antikoerper, AI450713 antikoerper, Dokl antikoerper, docking protein 3 antikoerper, DOK3 antikoerper, Dok3 antikoerper

Hintergrund: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing.Synonyms: Docking protein 3, Downstream of tyrosine kinase 3

Gen-ID: 79930

NCBI Accession: NP_079148

UniProt: Q7L591