MARCH4 Antikörper (AA 300-350)

Produktnummer ABIN372267

Produktdetails anti-MARCH4 Antikörper

Target: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Bindungsspezifität: AA 300-350

Reaktivität: Human, Maus, Ratte, Hund, Huhn, Pferd, Opossum, Zebrafisch (Danio rerio), Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody recognizes Membrane-Associated Ring Finger 4 (MARCH4).

Kreuzreaktivität (Details): Species reactivity (expected):Chimpanzee, Chicken, Dog (Canine), Horse, Mouse, Opossum, Rat and ZebrafishSpecies reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 300-350 of human RNF174.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.05 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MARCH4

Target: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Andere Bezeichnung: MARCH4 / RNF174 (MARCH4 Produkte)

Synonyme: MARCH-IV antikoerper, RNF174 antikoerper, BC056494 antikoerper, mKIAA1399 antikoerper, MARCH4 antikoerper, si:ch211-239d11.2 antikoerper, membrane associated ring-CH-type finger 4 antikoerper, membrane-associated ring finger (C3HC4) 4 antikoerper, MARCH4 antikoerper, March4 antikoerper, march4 antikoerper

Hintergrund: MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: E3 ubiquitin-protein ligase MARCH4, KIAA1399, MARCH-IV, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174

Molekulargewicht: 46 kDa

Gen-ID: 57574

NCBI Accession: NP_065865

UniProt: Q9P2E8