KLRG1
(Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
Reaktivität
Maus
Wirt
Hamster
Klonalität
Monoklonal
Konjugat
Dieser KLRG1 Antikörper ist konjugiert mit PE
Applikation
Flow Cytometry (FACS)
Spezifität
This antibody reacts with Killer Cell Lectin-like Receptor G1 (KLRG1 formerly known as mouse MAFA or 2F1-Ag). It stains 30-60 % of NK1.1+CD3- splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). (Ref.1,5)
Produktmerkmale
Synonyms: KLRG1, CLEC15A, MAFA, MAFAL, Mast cell function-associated antigen, MAFA-like receptor,ITIM-containing receptor MAFA-L, Killer cell lectin-like receptor subfamily G member 1,C-type lectin domain family 15 member A
Immunogen
Activated NK (A-LAK) cells from B6 (H-2b) mice. (Ref. 1)
KLRG1
Reaktivität: Maus
FACS
Wirt: Hamster
Monoclonal
2F1
PE
Applikationshinweise
Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.1,5) Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.1 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
KLRG1
(Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
Killer cell lectin-like receptor G1 (KLRG1, formerly known as mouse MAFA or 2F1 Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. (Ref.1,2) These ITIMs interact with the SH2 domains of protein phosphatases such as SHP1. (Ref.3,4) Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors. (Ref.1)Synonyms: C-type lectin domain family 15 member A, CLEC15A, ITIM-containing receptor MAFA-L, KLRG1, Killer cell lectin-like receptor subfamily G member 1, MAFA, MAFA-like receptor, MAFAL, Mast cell function-associated antigen