SULT1C2
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/1,000. Western Blot: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
SULT1C2
(Sulfotransferase Family, Cytosolic, 1C, Member 2 (SULT1C2))
The 296-amino acid human SULTC1 protein, so named on the basis of its significant homology to a rat hepatic cytosolic sulfotranserase ST1C1, catalyzes the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters, and may be involved in the activation of carcinogenic hydroxylamines. This enzyme also shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). SULT1C1 is expressed as a 1.4-kb mRNA in adult human stomach, kidney, and thyroid, and in fetal kidney and liver. By functional characterization of recombinant protein, it has been shown that SULT1C1 catalyzes the sulfonation of p-nitrophenol and N-hydroxy-2-acetylaminofluorene, but not dopamine, 17-beta-estradiol, or dehydroepiandrosterone.Synonyms: ST1C2, Sulfotransferase 1C1, Sulfotransferase 1C2, humSULTC2