SERPINA1 Antikörper

Produktnummer ABIN356484

Produktdetails anti-SERPINA1 Antikörper

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Purified

Immunogen: Purified human ATT.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. FFPE tissue sections require antigen retriever (boiling tissue in 10 mM citrate pH 6.0 for10-20 minutes, followed by cooling at RT for 15-20 minutes). Recommended Positive Control: Human tonsil, liver.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Andere Bezeichnung: alpha-1-Antitrypsin (SERPINA1 Produkte)

Synonyme: AACT antikoerper, ACT antikoerper, GIG25 antikoerper, A1AT antikoerper, PI antikoerper, alpha-1-PI antikoerper, A1A antikoerper, AAT antikoerper, PI1 antikoerper, PRO2275 antikoerper, alpha1AT antikoerper, Pi antikoerper, Spi1 antikoerper, MGC64429 antikoerper, serpina1d antikoerper, Aps antikoerper, SERPINA3-5 antikoerper, serpin family A member 3 antikoerper, alpha-1-antiproteinase F precursor antikoerper, serpin family A member 1 antikoerper, alpha-1-antitrypsin antikoerper, calumenin antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antikoerper, SH2B adaptor protein 2 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog antikoerper, SERPINA3 antikoerper, LOC100008973 antikoerper, SERPINA1 antikoerper, LOC100328621 antikoerper, CALU antikoerper, Serpina1 antikoerper, serpina1.S antikoerper, serpina1 antikoerper, SPIA5 antikoerper, Sh2b2 antikoerper, Calu antikoerper, serpina1.L antikoerper

Hintergrund: Alpha-1-Antitrypsin (AAT) is a 51 kDa glycoprotein synthesized in the liver. It is a serum protease inhibitor in neutrophil elastase, collagenase and chymotrypsin. This protein is a serum trypsin inhibitor, the correct name is alpha-1-proteinase inhibitor (A1PI). Disorders of this enzyme include, deficiency, in a hereditary disorder, this causes degradation of lung tissue and causes pulmonary emphysema, it also causes chronic liver disease and hepatocarcinoma. AAT is present in normal liver cells, histocytes, monocytes and a variety of epithelial and mesenchymal tumors. Increase in serum levels of AAT is also reported in rheumatoid arthritis, bacterial infection, vasculistis and carcinomatosis.Synonyms: AAT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1

Gen-ID: 9606

UniProt: P01009