Synaptophysin Antikörper (C-Term)

Produktnummer ABIN356461

Produktdetails anti-Synaptophysin Antikörper

Target: Synaptophysin (SYP)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptophysin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody reacts with Synaptophysin in neuroendocrine neoplasm of neural as well as epithelial type. Cellular localization: Cytoplasmic.

Aufreinigung: Protein A Chromatography.

Immunogen: A synthetic peptide from C-terminus of Human Synaptophysin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry for Formalin-Fixed Paraffin Embedded (FFPE) Tissue Sections andFrozen Sections: Dilute 1/100-1/200 using polymer or streptavidin approx. Biotin system for 30 mins at RT. This antibody requires antigen retriever (boiling FFPE tissue sections in 10 mMcitrate buffer, pH 6.0 for 10-20 mins. followed by cooling at RT for 20 mins). Positive Control: Human pancreas or GI tumor.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 3.0 mg/mL

Buffer: 10 mM PO4, 150 mM NaCl, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Synaptophysin

Target: Synaptophysin (SYP)

Andere Bezeichnung: Synaptophysin / SYP (SYP Produkte)

Synonyme: syp-B antikoerper, xsypii antikoerper, MGC86267 antikoerper, MRXSYP antikoerper, A230093K24Rik antikoerper, AI848995 antikoerper, Syn antikoerper, p38 antikoerper, Syp1 antikoerper, mrxsyp antikoerper, syp antikoerper, xsypi antikoerper, synaptophysin S homeolog antikoerper, synaptophysin antikoerper, synaptophysin L homeolog antikoerper, synaptophysin a antikoerper, syp.S antikoerper, SYP antikoerper, syp antikoerper, Syp antikoerper, syp.L antikoerper, sypa antikoerper

Hintergrund: Synaptophysin is a synaptic vesicle glycoprotein with 4 transmembrane domain MW 38 kDa. Thisproteinis present in the membrane of neuronal presynaptic vesicles in brain, spinal cord, retina, vesicles of adrenal medulla, neuromuscular junctions, and endocrine cells. It is also expressed by neuroendocrine cells throughout the body, both normal and neoplastic. Synaptophysin is also marker of endocrine tumors. It is a useful marker for the identification of normal neuroendocrine cells and neuroendocrine neoplasms.Synonyms: Major synaptic vesicle protein p38, Neuroendocrine Marker

Gen-ID: 6855

NCBI Accession: NP_003170

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity