IHC, WB. A concentration of 10-50 μg,ml recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handhabung
Avoid freeze and thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit
12 months
Target
Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)
2900073D12Rik antikoerper, DNPI antikoerper, VGLUT2 antikoerper, VGluT2 antikoerper, Dnpi antikoerper, Vglut2 antikoerper, VGLUT2.1 antikoerper, blu antikoerper, si:packt73.2 antikoerper, si:packt90.2 antikoerper, si:xx-packt73.2 antikoerper, slc17a6 antikoerper, vglut2a antikoerper, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 antikoerper, solute carrier family 17 member 6 antikoerper, solute carrier family 17 (vesicular glutamate transporter), member 6b antikoerper, Slc17a6 antikoerper, SLC17A6 antikoerper, slc17a6b antikoerper
Hintergrund
FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane, Multi-pass membrane protein. Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in brain. Expressed in hippocampal neurons (at protein level). DEVELOPMENTAL STAGE: Expressed in brain throughout development. Transiently expressed in hippocampal neurons during the first week after birth, with expression decreasing thereafter. MISCELLANEOUS: Mice lacking this protein exhibit an elevated rate of perinatal lethality. Surviving animals display a strong reduction in evoked glutamergic responses in thalamic neurons. Reduction of protein level in homozygous and heterozygous knockouts leads to a graded reduction in the amplitude of the postsynaptic response to single vesicle fusion in thalamic neurons, consistent with a role for this protein in determining quantal size.,SLC17 Family,Vesicular glutamate transporter 2, VGlU2, Solute carrier family 17 member 6, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Differentiation-associated BNPI, Slc17a6, Dnpi