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Histone 3 Antikörper (H3K36me3)

Name: Histone 3 Antikörper (H3K36me3)
SKU: ABIN3434046
Price: 800.46 EUR
Availability: InStock

H3 Reaktivität: Human, Maus WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN Wirt: Kaninchen Polyclonal unconjugated

Western Blot: Nuclear extract of HeLa cells (20 µg) probed with the Histone H3 trimethyl Lys36 antibody at a dilution of 1 µg/ml.

ChIP

ChIP-seq

Histone H3K36me3 antibody (pAb) tested by immunofluorescence.

Specificity Data: Dot blot analysis was used to confirm the specificity of Histone H3 trimethyl Lys36 antibody for trimethyl-lysine 36 of histone H3.

5 Abbildungen

(5 Referenzen)

Produktnummer ABIN3434046

Datenblatt (PDF)

Target Alle Histone 3 (H3) Antikörper anzeigen

Histone 3 (H3)
Bindungsspezifität
63

47

46

45

41

37

36

35

35

35

34

32

31

29

29

29

26

25

23

23

22

22

20

18

18

17

17

16

16

16

16

16

15

14

14

13

13

12

12

12

12

12

11

11

10

10

10

9

9

8
H3K36me3
Reaktivität
1407

941

862

59

42

41

41

40

39

35

35

30

30

22

19

6

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Human, Maus
Wirt
1217

247

12

4
Kaninchen
Passende Sekundärantikörper
Klonalität
1120

359

1
Polyklonal
Konjugat
823

81

65

64

63

63

63

62

37

33

24

17

17

17

17

17

14

2

1
Dieser Histone 3 Antikörper ist unkonjugiert
Applikation
1058

411

378

313

251

188

186

179

163

160

141

126

119

48

38

34

32

20

15

14

7

7

6

4

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)

Aufreinigung

Protein A Chromatography

Immunogen

This Histone H3 trimethylLys36 antibody was raised against a peptide containing trimethylLys36 of human histone H3.

Isotyp

IgG

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anti-Histone 3 (H3) (H3K4me3) antibody
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anti-Histone 3 (H3) (C-Term) antibody
H3 Reaktivität: Human WB, IHC, ChIP, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Histone 3 (H3) (H3K4me3) antibody
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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 μg/μL

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung

-20 °C

Informationen zur Lagerung

Antibodies in solution can be stored at -20 °C for 2 years.

Haltbarkeit

6 months
Powers, Parvanov, Baker, Walker, Petkov, Paigen: "The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo." in: PLoS genetics, Vol. 12, Issue 6, pp. e1006146, (2016) (PubMed).

Ho, Nateras, Yan, Park, Jensen, Borges, Lee, Champion, Tibes, Bryce, Carballido, Todd, Joseph, Wong, Parker, Stanton, Castle: "A Multidisciplinary Biospecimen Bank of Renal Cell Carcinomas Compatible with Discovery Platforms at Mayo Clinic, Scottsdale, Arizona." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132831, (2015) (PubMed).

Pham, Inoue, Vu, Nguyen, Nakayashiki, Ikeda, Nakayashiki: "MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005385, (2015) (PubMed).

Feng, Zhang, Shea, Creighton, Coarfa, Hilsenbeck, Lanz, He, Wang, Fu, Nardone, Song, Bradner, Mitsiades, Mitsiades, Osborne, Schiff, OMalley: "An epigenomic approach to therapy for tamoxifen-resistant breast cancer." in: Cell research, Vol. 24, Issue 7, pp. 809-19, (2014) (PubMed).

Mews, Zee, Liu, Donahue, Garcia, Berger: "Histone methylation has dynamics distinct from those of histone acetylation in cell cycle reentry from quiescence." in: Molecular and cellular biology, Vol. 34, Issue 21, pp. 3968-80, (2014) (PubMed).
Target

Histone 3 (H3)

Andere Bezeichnung

Histone H3 (H3 Produkte)

Synonyme

H-3 antikoerper, histocompatibility 3 antikoerper, H3 antikoerper

Molekulargewicht

17 kDa

Gen-ID

3020