MTA2 Antikörper (AA 652-668)
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- Target Alle MTA2 Antikörper anzeigen
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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Bindungsspezifität
- AA 652-668
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MTA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- Recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. Does not cross-react with MTA1.
- Aufreinigung
- Immunoaffinity purified
- Immunogen
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Peptide corresponding to aa 652-668 of human PID/MTA2. This sequence differs from that of mouse by one amino acid.
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product MTA2 Primärantikörper
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- Applikationshinweise
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Approved: WB (0.5 - 1 μg/mL)
Usage: Western Blot: A band of 75 kD is detected. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
- Andere Bezeichnung
- MTA2 (MTA2 Produkte)
- Synonyme
- MTA1L1 antikoerper, PID antikoerper, fd61b05 antikoerper, wu:fd61b05 antikoerper, wu:fi29g02 antikoerper, zgc:63487 antikoerper, pid antikoerper, mta1l1 antikoerper, MTA2 antikoerper, DKFZp470E0911 antikoerper, AW550797 antikoerper, Mata1l1 antikoerper, Mta1l1 antikoerper, mmta2 antikoerper, metastasis associated 1 family member 2 antikoerper, metastasis associated 1 family, member 2 antikoerper, metastasis-associated gene family, member 2 antikoerper, metastasis associated 1 family member 2 L homeolog antikoerper, MTA2 antikoerper, mta2 antikoerper, Mta2 antikoerper, mta2.L antikoerper
- Hintergrund
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Name/Gene ID: MTA2
Synonyms: MTA2, Metastasis-associated 1-like 1, MTA1L1, PID, MTA1-L1, MTA1-L1 protein - Gen-ID
- 9219
- UniProt
- O94776
- Pathways
- Chromatin Binding
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