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eIF4EBP1 Antikörper
EIF4EBP1
Reaktivität: Human
WB, IHC, ELISA
Wirt: Maus
Monoclonal
11G12C11
unconjugated
Produktnummer ABIN3209983
Produktdetails anti-eIF4EBP1 Antikörper
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Target
Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigen
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Reaktivität
Alle Reaktivitäten für eIF4EBP1 Antikörper
Human
Wirt
Alle Wirte für eIF4EBP1 Antikörper
Maus
Klonalität
Alle Klonalitäten für eIF4EBP1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für eIF4EBP1 Antikörper
Dieser eIF4EBP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für eIF4EBP1 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Aufreinigung
Purified antibody.
Immunogen
4 EBP1 antibody was raised in Mouse using a purified recombinant fragment of 4 BP1 expressed in E. coli as the immunogen.
Klon
11G12C11
Isotyp
IgG1
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Discover our top product EIF4EBP1 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
Lot specific
Buffer
Purified antibody supplied in PBS containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Details zu eIF4EBP1
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Target
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Andere Bezeichnung
4EBP1 (EIF4EBP1 Produkte )
Synonyme
4E-BP1 antikoerper, 4EBP1 antikoerper, BP-1 antikoerper, PHAS-I antikoerper, 4e-bp1 antikoerper, AA959816 antikoerper, 153432_at antikoerper, 43-BP antikoerper, 4E-BP antikoerper, 4EBP antikoerper, 4e-bp antikoerper, 4eBP antikoerper, 4ebp antikoerper, BcDNA.HL08053 antikoerper, BcDNA:HL08053 antikoerper, CG8846 antikoerper, CT8705 antikoerper, Dm 4E-BP antikoerper, Dmel\\CG8846 antikoerper, Phas1 antikoerper, Thor/EIF4EBP antikoerper, anon-WO0172774.158 antikoerper, d4E-BP antikoerper, d4E-BP1 antikoerper, d4EBP antikoerper, d4e-bp antikoerper, d4eBP antikoerper, dthor antikoerper, eIF4E-BP antikoerper, l(2)06270 antikoerper, l(2)k07736 antikoerper, l(2)k13517 antikoerper, pp20 antikoerper, thor antikoerper, EIF4EBP1 antikoerper, fc04h09 antikoerper, wu:fc04h09 antikoerper, zgc:64137 antikoerper, eukaryotic translation initiation factor 4E binding protein 1 antikoerper, CG8846 gene product from transcript CG8846-RA antikoerper, EIF4EBP1 antikoerper, Eif4ebp1 antikoerper, Thor antikoerper, eif4ebp1 antikoerper
Hintergrund
4EBP1 which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. 4EBP1 functions as a translation repressor. Synonyms: Monoclonal 4EBP1 antibody, Anti-4EBP1 antibody, 4E-BP1 antibody, 4E BP1 antibody, Eukaryotic translation initiation factor 4E-binding protein 1 antibody, BP-1 antibody, MGC4316 antibody.
Pathways
MAPK Signalweg , PI3K-Akt Signalweg , RTK Signalweg , AMPK Signaling , Regulation of Cell Size , BCR Signaling
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