PPP1R3C Antikörper

Produktnummer ABIN317934

Produktdetails anti-PPP1R3C Antikörper

Target: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R3C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of PTG protein.(region surrounding Lys75)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PPP1R3C

Target: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Andere Bezeichnung: PPP1R3C / PTG (PPP1R3C Produkte)

Synonyme: PPP1R5 antikoerper, PTG antikoerper, Ppp1r5 antikoerper, R5 antikoerper, ppp1r3c antikoerper, zgc:73259 antikoerper, cb444 antikoerper, fc19f02 antikoerper, sb:cb444 antikoerper, wu:fb50a11 antikoerper, wu:fc17c07 antikoerper, wu:fc19f02 antikoerper, zgc:92069 antikoerper, protein phosphatase 1 regulatory subunit 3C antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 3C antikoerper, protein phosphatase 1, regulatory subunit 3C antikoerper, protein phosphatase 1, regulatory subunit 3Cb antikoerper, protein phosphatase 1, regulatory subunit 3Ca antikoerper, PPP1R3C antikoerper, Ppp1r3c antikoerper, ppp1r3cb antikoerper, ppp1r3c antikoerper, ppp1r3ca antikoerper

Hintergrund: Protein phosphatase 1 (PP1) is a serine-threonine protein phosphatase that plays a central role in mediating the effects of insulin on glucose and lipid metabolism. PTG (protein targeting to glycogen) was cloned from 3T3-L1 adipocytes as a protein that binds to the PP1 catalytic subunit. The human homolog of PTG, designated PPP1R5, has been shown to bind to PP1 and to modulate its specificity. PTEN/PPP1R5 shows 42 % identity to the glycogen binding subunit, G(L), of rat liver PP1. PTG is expressed predominantly in insulin-sensitive tissues, and it localizes PP1 to glycogen. PTG also has been shown to interact with several enzymes involved in the hormonal regulation of glycogen metabolism, including phosphorylase kinase, phosphorylase A and glycogen synthase. These data indicate a role for PTG in glycogen metabolism, possibly that of a molecular scaffold.Synonyms: PPP1R5, Protein phosphatase 1 regulatory subunit 3C, Protein phosphatase 1 regulatory subunit 5, Protein targeting to glycogen

Molekulargewicht: approx. 36 kDa

Gen-ID: 5507

NCBI Accession: NP_005389

UniProt: Q9UQK1

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process