SERPINA5 Antikörper

Produktnummer ABIN317849

Produktdetails anti-SERPINA5 Antikörper

Target: SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: PAI-3 antibody detects endogenous levels of PAI-3 protein.(region surrounding Leu291)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SERPINA5

Target: SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))

Andere Bezeichnung: SERPINA5 (SERPINA5 Produkte)

Synonyme: 4933415L04 antikoerper, PAI-3 antikoerper, Pci antikoerper, PAI3 antikoerper, PCI antikoerper, PCI-B antikoerper, PLANH3 antikoerper, PROCI antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antikoerper, serpin family A member 5 antikoerper, serine (or cysteine) peptidase inhibitor, clade A, member 5 antikoerper, plasma serine protease inhibitor antikoerper, SPIA5 antikoerper, SERPINA5 antikoerper, Serpina5 antikoerper, LOC480424 antikoerper

Hintergrund: PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.Synonyms: Acrosomal serine protease inhibitor, PAI-3, PAI3, PCI, PLANH3, PROCI, Plasma serine protease inhibitor, Plasminogen activator inhibitor 3, Protein C inhibitor, Serpin A5

Molekulargewicht: approx. 42 kDa

Gen-ID: 5104

NCBI Accession: NP_000615

UniProt: P05154