GRID2 Antikörper

Produktnummer ABIN317812

Produktdetails anti-GRID2 Antikörper

Target: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRID2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous levels of GluR delta-2 protein.(region surrounding Gly860)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/20000 - 1/40000. Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRID2

Target: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Andere Bezeichnung: Glutamate Receptor delta-2 (GRID2 Produkte)

Synonyme: GluD2 antikoerper, glurd2 antikoerper, si:rp71-1l7.1 antikoerper, GRID2 antikoerper, B230104L07Rik antikoerper, GluRdelta2 antikoerper, Lc antikoerper, Lc antikoerper, MMS10-AC antikoerper, Ms10ac antikoerper, cpr antikoerper, ho antikoerper, nmf408 antikoerper, tpr antikoerper, glutamate receptor, ionotropic, delta 2 antikoerper, glutamate receptor ionotropic, delta-2 antikoerper, glutamate ionotropic receptor delta type subunit 2 antikoerper, grid2 antikoerper, LOC704787 antikoerper, GRID2 antikoerper, Grid2 antikoerper, LOC536367 antikoerper

Hintergrund: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR-δ2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four ε subunits display limited distribution. In mice, mutations in the gene encoding GluR-δ2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR-δ2 maps to chromosome 4q22.Synonyms: GLURD2, GRID2, GluR delta-2

Molekulargewicht: approx. 113 kDa

Gen-ID: 2895

NCBI Accession: NP_001501

UniProt: O43424

Pathways: Synaptic Membrane