KIR5.1 Antikörper

Produktnummer ABIN317797

Produktdetails anti-KIR5.1 Antikörper

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIR5.1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Kir5.1 antibody detects endogenous levels of Kir5.1 protein.(region surrounding asn410)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KIR5.1

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Andere Bezeichnung: KCNJ16 (KCNJ16 Produkte)

Synonyme: kcnj16-A antikoerper, Kir5.1 antikoerper, KCNJ16 antikoerper, BIR9 antikoerper, KIR5.1 antikoerper, 6430410F18Rik antikoerper, AI132396 antikoerper, potassium channel, inwardly rectifying subfamily J, member 16 S homeolog antikoerper, potassium voltage-gated channel subfamily J member 16 antikoerper, potassium channel, inwardly rectifying subfamily J, member 16 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 16 antikoerper, kcnj16.S antikoerper, KCNJ16 antikoerper, kcnj16 antikoerper, Kcnj16 antikoerper

Hintergrund: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as KIR1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as KIR1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down's syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.Synonyms: Inward rectifier K(+) channel Kir5.1, Inward rectifier potassium channel 16, KCNJ16, Potassium channel, inwardly rectifying subfamily J member 16

Molekulargewicht: approx. 48 kDa

Gen-ID: 3773

NCBI Accession: NP_061128

UniProt: Q9NPI9